Reproducibility and standardization in Radiomics: Are we there yet?

Radiomics aims for ways to personalize patient's treatments based on the extraction of texture features from routine clinical images. However, implementation Radiomics-based models in patient care poses a significant number challenges, since there are multi-step processes model. These include image selection (e.g CT, MRI, PET, or combination these), region interest (ROI) segmentation, texture-feature extraction, model development, and model-validation. Each these needs careful evaluation ensure reproducibility accuracy final before it can be introduced into practice. Image selection, ROI feature most critical component modeling, because they define reliability In this short review, after presenting brief description representative workflow, we will concentrate particular status various technical aspects imaging modality, segmentation including their shortcomings possible solutions with emphasis radiation therapy.